|
|
8,11,14-eicosatrienoic_acid + O2 + ferricytochrome_b5 + H+ <=> Arachidonoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
| |
BRENDA:
BR51508;
BS433635
KEGG:
R11059
MetaCyc:
RXN-16064
|
|
|
|
(11Z,14Z)-icosa-11,14-dienoyl-CoA + NADP+ <=> (2E,11Z,14Z)-icosatrienoyl-CoA + NADPH + H+
|
1.3.1.93
very-long-chain enoyl-CoA reductase
|
–
|
| |
MetaCyc:
RXN-16097
|
|
|
|
(3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA <=> (2E,11Z,14Z)-icosatrienoyl-CoA + H2O
|
4.2.1.134
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
|
–
|
| |
MetaCyc:
RXN-16096
|
|
|
|
(11Z,14Z)-icosa-11,14-dienoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> 8,11,14-eicosatrienoic_acid + H2O + ferricytochrome_b5
|
1.14.19
1.14.19.3
acyl-CoA 6-desaturase
|
–
–
|
| |
KEGG:
R12171
MetaCyc:
RXN-17105
|
|
|
|
(3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA + NADP+ <=> (11Z,14Z)-3-oxoicosadienoyl-CoA + NADPH + H+
|
1.1.1.330
very-long-chain 3-oxoacyl-CoA reductase
|
–
|
| |
MetaCyc:
RXN-16095
|
|
|
|
malonyl-CoA + linoleoyl-CoA + H+ <=> (11Z,14Z)-3-oxoicosadienoyl-CoA + CO2 + CoA
|
2.3.1.199
very-long-chain 3-oxoacyl-CoA synthase
|
–
|
| |
MetaCyc:
RXN-16094
|
|
